2-methylene-5-substituted-methylenecyclopentanone derivatives and use thereof
The invention relates to 2-methylene-5-substituted-methylenecyclopentanone derivatives of formula I, and the use thereof. The derivatives of formula I as active components are useful for preparing a...
View ArticleMethod for monitoring, diagnosing, and screening cancer through measuring the...
The present invention relates to a method for diagnosis and screening of cancer by measuring the expression of des-R prothrombin activation peptide fragment F2 (des-R F2) in serum, more precisely,...
View ArticleLactone formulations and method of use
wherein R1-R9 and Y1-Y3 taken independently are preferably a hydrogen atom, a halogen atom, a hydroxyl group, or any other organic groups or groupings which optionally include a heteroatom such as...
View ArticleVhz for diagnosis and treatment of cancers
We provide VHZ for use in a method of treatment, prophylaxis or alleviation of a cancer in an individual selected from the group consisting of: colon cancer, lung cancer, squamous cell carcinoma...
View ArticleCst1, dcc1, ifitm1 or melk as markers for diagnosing stomach cancer
The present invention relates to a biomarker for gastric cancer, CST1 (cysteine proteinase inhibitor, type 2 family), DCC1 (Defective in sister chromatid cohesion homolog 1), IFITM1 (interferon...
View ArticleInhibitors of c-fms kinase
wherein Z, X, J, R2 and W are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially...
View ArticlePolypeptides and polynucleotides for artemin and related ligands, and methods...
The invention encompasses polypeptides, polynucleotides, and antibodies, for Artemin and related ligands, including Persephin (PSPN). The invention also encompasses expression vectors and host cells...
View ArticlePharmaceutical being used for treating cancer and fibrosis disease and the...
Provided is the composition of a peptide and its mutagenic version, or other derivatives with the same 3-D structure with activity to bind the extracellular domain of PDGFR-α, or -β, but does not...
View ArticleDeuterium-enriched pyrimidine compounds and derivatives
for the prevention and treatment of cancer including brain cancer, breast cancer, blood cancer, colorectal cancer, lung cancer, liver cancer, ovarian cancer, pancreas cancer, prostate cancer, stomach...
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